| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Amphiphysin |
|---|
| Clone | N8-2 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 1:100, Immunoprecipitation: 2 µg, Western Blot: 0.1 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Amphiphysin Monoclonal Antibody (N8-2). Amphiphysins, members of the BAR (Bin-Amphiphysin-Rvsp) protein super family, play a key role in clathrin-mediated endocytosis of synaptic vesicles (SVs). All members of the BAR family share a highly conserved N-terminal BAR domain and a C-terminal Src homology (SH3) domain. Two isoforms of amphiphysin have been identified and act in concert as a heterodimer. Amphiphysins interact via its carboxy-terminal SH3 domain with dynamin, synaptojanin and clathrin. These complexes are implicated in synaptic vesicle recycling at nerve terminal. Amphiphysins were also identified as the dominant autoantigen in paraneoplastic Stiff-Man Syndrome. |
|---|
| Immunogen | n/a |
|---|
| Other Names | AMPH; AMPH1; Stiff Man syndrome with breast cancer 128kDa autoantigen |
|---|
| Gene, Accession # | Entrez: 218038, 273, 60668; Uniprot: O08838, P49418, Q7TQF7 |
|---|
| Catalog # | MA5-17205 |
|---|
| Price | |
|---|
| Order / More Info | Amphiphysin Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|