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| Product Name | Oncostatin M, Recombinant, Human, aa26-234, His-Tag (OSM) |
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| Description | Purity ~95% (SDS-PAGE). Purified by conventional chromatography techniques. OSM, also known as Oncostatin M, is a pleiotropic cytokine that belongs to the interleukin 6 group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. However, it is as yet poorly defined and is proving important in liver development, haematopoeisis, inflammation and possibly CNS development. It is also associated with bone formation and destruction. OSM signals through cell surface receptors that contain the protein gp130. The type I receptor is composed of gp130 and LIFR, the type II receptor is composed of gp130 and OSMR. Recombinant protein corresponding to aa26-234 of human OSM, fused with His-tag at N-terminus, expressed in E.coli (NP_065391). AA sequence: MGSSHHHHHH SSGLVPRGSH MAAIGSCSKE YRVLLGQLQK QTDLMQDTSR LLDPYIRIQG LDVPKLREHC RERPGAFPSE ETLRGLGRRG FLQTLNATLG CVLHRLADLE QRLPKAQDLE RSGLNIEDLE KLQMARPNIL GLRNNIYCMA QLLDNSDTAE PTKAG |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_065391 |
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| Catalog # | O6500-02A |
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| Order / More Info | Oncostatin M, Recombinant, Human, aa26-234, His-Tag (OSM) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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