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| Product Name | VEGF-D, Recombinant, Human (Vascular Endothelial Growth Factor-D, FIGF) |
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| Description | Purity ≥95% by SDS-PAGE gel and HPLC analyses. VEGF-D, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability.VEGF-D is highly expressed in the lung, heart, small intestine and fetal lung, and at lower levels in the skeletal muscle, colon, and pancreas.It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-D may play a role in the formation of the venous and lymphatic vascular systems.It also participates in the growth and maintenance of differentiated lymphatic endothelium in adults.Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis.Recombinant human VEGF-D is a 26.2kD non-disulfide linked homodimer |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143541 |
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| Order / More Info | VEGF-D, Recombinant, Human (Vascular Endothelial Growth Factor-D, FIGF) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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