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| Product Name | Human CellExp™ Osteoactivin / GPNMB, human recombinant |
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| Description | Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages. This protein is fused with 6xHis tag at the C-terminus, has a calculated MW of 52.9 kDa. The predicted N-terminus is Ala 22. DTT-reduced Protein mi |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | GPNMB, HGFIN, NMB, Osteoactivin |
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| Gene, Accession, CAS # | GPNMB, Gene ID: 10457, Accession: Q96F58 |
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| Catalog # | 7513-10 |
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| Price | |
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| Order / More Info | Human CellExp™ Osteoactivin / GPNMB, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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