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Product Name | Pim 1, Active |
Description | The proto-oncogene Pim1 belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Originally identified from Moloney murine leukemia virus induced T-cell lymphomas in mice, Pim1 is involved in the control of cytokine-mediated cell proliferation, differentiation and survival of lymphoid and myeloid cells as well as others. Expression of Pim1 can be stimulated by a variety of growth factors and is regulated at four different levels: transcriptional, post-transcriptional, translational and post-translational. Accumulating data support that the expression of Pim1 is mediated through activation of the JAK/STAT pathway. Some of the substrates of Pim1 include p21 Cip1, nuclear m |
Size | 5 µg |
Concentration | 5µg/50 µl |
Applications | RUO |
Other Names | Pim, Serine/threonine-protein kinase Pim-1 |
Gene, Accession, CAS # | PIM1, Gene ID: 5292, Accession: P11309 |
Catalog # | 7742-5 |
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Order / More Info | Pim 1, Active from BIOVISION, INC. |
Product Specific References | n/a |
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