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| Product Name | RAF 265 |
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| Description | Raf kinase and VEGFR-2 inhibitor. Inhibits c-Raf, wild type B-Raf and mutant B-Raf (V600E). Cytotoxic in certain melanoma cells lines. Effects enhanced by protein kinase D3 inhibition, preventing reactivation of MAPK signaling and increasing caspase activity. Orally bioavailable. Purity 98%. MW (observed): 518.41 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-Methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine. CHIR 265 |
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| Gene, Accession, CAS # | CAS: 927880-90-8 |
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| Catalog # | 6015/50 |
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| Order / More Info | RAF 265 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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