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| Product Name | CD154 CD8a, Fusion Protein |
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| Description | Purified by affinity chromatography. Human CD154 (CD40 Ligand) is a member of the tumor necrosis factor (TNF) family and is expressed on the surface of activated T cells. It can undergo proteolytic cleavage into a 19kD immunologically active soluble form. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function. Increased levels of CD154 has been associated with autoimmune disorders including SLE, CLL and eosinophilic fasciitis. CD154 has been reported to be expressed on vascular endothelial cells, smooth muscle cells, macrophages and activated platelets indicating a role for the CD40-CD154 immunoregulatory signaling in arthrosclerosis and cardiovascular disorders. Applications: Suitable for use in Flow Cytometry, ELISA and Western Blot. |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | ELISA FC WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2548-84N6 |
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| Order / More Info | CD154 CD8a, Fusion Protein from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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