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| Product Name | CADM1, 45-374aa, Human, His tag, E Coli |
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| Description | MW: 39.4 kDa (353aa) confirmed by MALDI-TOF. Purity >85% by SDS-PAGE. CADM1 mediates homophilic cell-cell adhesion in a Ca2+-independent manner and also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca2+-independent manner. This protein acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated reject |
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| Size | 0.02 mg, 0.1 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Cell adhesion molecule 1; BL2; IGSF4; IGSF4A; Necl-2; NECL2; RA175; sgIGSF; ST17; sTSLC-1; SYNCAM; synCAM1; TSLC1] |
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| Gene, Accession, CAS # | CADM1, Gene ID: 23705, Accession: NP_055148 |
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| Catalog # | MBS206025 |
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| Order / More Info | CADM1, 45-374aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Barton C.H., et al. (1988) Development 104:165-173. |
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