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| Product Name | BAG3, 1-575aa, Human, His tag, E Coli |
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| Description | MW: 63.7 kDa (595aa). Purity >90% by SDS-PAGE. BAG3 was reported initially as a protein-refolding cochaperone of the bcl2 binding protein BAG family and as upregulated in response to persistent stress of cellular calcium balance dysregulation. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [BAG family molecular chaperone regulator 3; BIS; CAIR-1; BAG family molecular chaperone regulator 3 BAG 3; Bcl 2 binding protein; BCL2 associated athanogene 3; BCL2 binding athanogene 3; Docking protein CAIR 1.] |
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| Gene, Accession, CAS # | BAG3, Gene ID: 9531, Accession: NP_004272 |
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| Catalog # | MBS203482 |
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| Order / More Info | BAG3, 1-575aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Virador VM., et al. (2009) PLos One. 4 (4):e5136. ; Kyratsous CA., et al. (2008) Proc Natl Acad Sci u S A. 105 (52):20912-7.; |
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