| 产品详情 |
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| Product Name | 7-Azido-4-methylcoumarin (AzMC) |
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| Description | Purity ~98% (H-NMR, MS). Highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4- methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex=365nm and lambdaem=450nm. Photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). Probe to monitor the enzymatic production of H2S in vitro and to visualize H2S in living cells. Tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)). Tool to identify novel cystathionine beta-synthase (CBS) inhibitors and activators. Suitable for high-throughput screening. Use of this product with DTT, TCEP and/or biological thiols at concentrations of >25mM should be avoided for maximum efficiency. Formula: C10H7N3O2 Solubility: DMSO Molecular Weight: ~201.2 |
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| Size | 1mg, 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207024 |
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| Order / More Info | 7-Azido-4-methylcoumarin (AzMC) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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