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Product Name | PBEF, Recombinant, Human |
Description | Purity ≥ 98% by SDS-PAGE and HPLC analyses. Endotoxin:≤ 0.1ng/ug (1EU/ug). Visfatin is a 55kD protein produced and secreted primarily by white adipose tissue. Recently, Visfatin was isolated from visceral fat deposits and shown to possess insulin-mimetic activity. Like insulin, Visfatin exerts hypoglycemic effects by interacting with the insulin receptor. The binding affinity of Visfatin for the insulin receptor is similar to that of insulin, but it does not compete with insulin, suggesting that the two proteins interact with different receptor sites. The circulating levels of Visfatin are much lower than those of insulin and are not affected by feeding, implying that the hypoglycemic effect of Visfatin may not be of physiological importance. The plasma Visfatin levels, like those of Leptin, correlate positively with the percent of body fat and increase during the development of obesity. Another similarity between Visfatin and Leptin is that their amino acid sequence is highly conserv |
Size | 5ug, 25ug |
Concentration | n/a |
Applications | n/a |
Other Names | PBEF, Recombinant, Human (Pre-B cell Colony Enhancing Factor, Pre-B cell Enhancing Factor, 1110035O14Rik, DKFZP666B131, EC 2.4.2.12, MGC117256, Nicotinamide Phosphoribosyltransferase, NAmPRTase, NAMPT, Pre-B cell Colony Enhancing Factor 1, PBEF1, Visfatin) |
Gene, Accession, CAS # | Accession: NP_005737 |
Catalog # | P3113-97R |
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Order / More Info | PBEF, Recombinant, Human from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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