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| Product Name | JW 55 |
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| Description | Inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). Activity results in stabilization of Axin2 and increased degradation of β-catenin; inhibits the β-catenin signaling pathway. Also shown to decrease canonical Wnt signaling in SW480 and HCT-15 colon carcinoma cell lines; reduces cell cycle progression and proliferation in SW480 cells in vitro. Purity 98%. MW (observed): 434.48 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[4-[[[[Tetrahydro-4-(4-methoxyphenyl)-2H-pyran-4-yl]methyl]amino]carbonyl]phenyl]-2-furancarboxamide |
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| Gene, Accession, CAS # | CAS: 664993-53-7 |
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| Catalog # | 4514/10 |
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| Price | |
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| Order / More Info | JW 55 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25568183 |
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