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Product Name | Antibiotic UCN-01 (7-Hydroxystaurosporine, UCN-01) |
Description | Purity ≥98% by HPLC. Isolated from Streptomyces sp., Antibiotic UCN-01 inhibits protein kinase C (PKC) and cyclin-dependent kinase 2 (CDK2) resulting in accumulation of cells in the G1 phase and induction of apoptosis. UCN-01 also enhances the cytotoxicity of other anti-cancer drugs, such as DNA-damaging agents and anti-metabolite drugs, through putative abrogation of G2 and/or S phase accumulation induced by these anti-cancer agents. Solubility: Soluble in ethyl ethanol, DMF or DMSO. |
Size | 1mg |
Concentration | n/a |
Applications | n/a |
Other Names | 7-Hydroxystaurosporine, UCN-01 |
Gene, Accession, CAS # | n/a |
Catalog # | A2297-39 |
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Order / More Info | Antibiotic UCN-01 (7-Hydroxystaurosporine, UCN-01) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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