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| Product Name | Jagged-2, Recombinant, Mouse,Fc (Protein Jagged-2, hJ2, JAG2) |
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| Description | Purity >90% (SDS-PAGE). Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showed in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development. Sequence: Extracellular domain of mouse Jagged-2 (aa 24-1082) is fused at the C-terminus to the Fc portion of human IgG. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Protein Jagged-2, hJ2, JAG2 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 44971 |
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| Order / More Info | Jagged-2, Recombinant, Mouse,Fc (Protein Jagged-2, hJ2, JAG2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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