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Product Name | CADM1, Recombinant, Human, aa45-374, His-Tag |
Description | Purity ~85% (SDS-PAGE). CADM1 mediates homophilic cell-cell adhesion in a Ca2+-independent manner and also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca2+-independent manner. This protein acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. Source: Recombinant protein corresponding to aa45-374 from human CADM1, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~39.4kD (353aa) Applications: Suitable for use in SDS-PAGE. |
Size | 20ug, 100ug |
Concentration | n/a |
Applications | n/a |
Other Names | CADM1, Recombinant, Human, aa45-374, His-Tag (Cell Adhesion Molecule 1, Immunoglobulin Superfamily Member 4, BL2, IGSF4, IGSF4A, Necl-2, NECL2, RA175, SgIGSF, ST17, STSLC-1, SYNCAM, SynCAM1, TSLC1) |
Gene, Accession, CAS # | Accession: NP_055148 |
Catalog # | 217988 |
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Order / More Info | CADM1, Recombinant, Human, aa45-374, His-Tag from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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