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| Product Name | Human CellExp™ CD33 / SIGLEC-3, human recombinant |
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| Description | Myeloid cell surface antigen CD33 also known as SIGLEC3, Siglecs (sialic acid binding Ig-like lectins) and GP67, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Human CD33 / Siglec-3 cDNA encodes a 364 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N--terminal Ig--like V--type domain, one Ig--like C2--type domains, a transmembrane region and a cytoplasmic tail. CD33 / Siglec-3 usually considered myeloid-specific, but it can also be found on some lymphoid cells. In the immune response, CD33 / Siglec-3 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via thei |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | CD33, SIGLEC3, gp67 |
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| Gene, Accession, CAS # | CD33, Gene ID: 945, Accession: P20138 |
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| Catalog # | 7370-50 |
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| Order / More Info | Human CellExp™ CD33 / SIGLEC-3, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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