| 产品详情 |
| Edit |   |
|---|
| Product Name | EHop-016 |
|---|
| Description | A Rac1 and Rac3 inhibitor; inhibits Rac1 activity (IC50 = 1.1 µM); inhibits Rac3 activity (58% at 1 µM); inhibits Cdc42 activity (28% at ≥ 5 µM); increases RhoA activity (1.3-fold at ≥2 µM); increases Rac-regulated lamellipodia formation and PAK1-mediated cell migration in MDA-MB-435 cells (2-4 µM); lowers mammary fat pad tumor growth, metastasis, and angiogenesis in a nude mouse model of breast cancer (25 mg/kg); inhibits mutant KIT-induced growth in systemic mastocytosis and AML cells (≥2.5 µM) |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Rac-1 3 EHop016 Cdc-42 MDAMB-435 MDAMB435 PAK-1 Rho-A |
|---|
| Gene, Accession, CAS # | CAS: 1380432-32-5 |
|---|
| Catalog # | 21557-10 |
|---|
| Price | |
|---|
| Order / More Info | EHop-016 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|