| 产品详情 |
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| Product Name | Amylin, aa1-37, Rat, Oxidized |
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| Description | Purified (~97%). The calcitonin family of bioactive peptides comprises of calcitonin, amylin, two calcitonin-gene related peptides (CGRP1, and CGRP2) and adrenomedullin (ADM). Amylin is a 37aa peptide produced in the pancreatic beta- cell secretory granules and is co-released with insulin. Amylin also has CGRP-like effects on bone metabolism. Amylin has specific binding sites in the CNS and it may regulate gastric emptying and influence carbohydrate metabolism. The calcitonin family peptides probably act through G-protein coupled membrane receptors. Recently, a homolog of calcitonin receptor, CRLR (calcitonin- receptor-like receptor human 461aa; rat/mouse 463aa) was identified. It is now shown that CRLR can function as either a CGRP receptor or an ADM receptor, depending upon which members of a new family of proteins called receptor activity modifying proteins (RAMP1-3) are expressed. Source: Full length rat amylin 1-37aa, amdie. AA Sequence: Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg |
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| Size | 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Amylin, aa1-37, Rat, Oxidized (DAP, Diabetes-Associated Peptide, IAP, Islet Amyloid Polypeptide, Insulinoma Amyloid Peptide, IAPP) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A2275-53R |
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| Order / More Info | Amylin, aa1-37, Rat, Oxidized from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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