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| Product Name | Amylin, Recombinant, Human |
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| Description | Purity ~95% (RP-HPLC, SDS-PAGE). Amylin, or Islet Amyloid Polypeptide (IAPP), is a 37-residue peptide hormone secreted by pancreatic beta-cells at the same time as insulin (in a roughly 100:1 ratio). Amylin functions as part of the endocrine pancreas and contributes to glycemic control. Although amylin's complete function may not yet be known, it has been shown to slow gastric emptying, promote satiety, inhibit secretion of glucagon during hyperglycemia, and therein reduce the total insulin demand. As insulin lowers blood glucose and glucagon raises blood glucose, amylin supports the stability of blood glucose levels in effect by slowing the rate that digested glucose enters the bloodstream. Rodent amylin knockouts are known to fail to achieve the normal anorexia following food consumption. Because it is an amidated peptide, like many neuropeptides, it is believed to be responsible for the anorectic effect. It was identified independently by two groups as the major component of islet A |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Amylin, Recombinant, Human (DAP, IAP, Islet Amyloid Polypeptide, Diabetes-associated Peptide, Insulinoma Amyloid Peptide, IAPP) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208741 |
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| Order / More Info | Amylin, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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