| 产品详情 |
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| Product Name | 2,4-Pyridinedicarboxylic Acid |
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| Description | Purity ≥98%. MW: 167.12. 2,4-Pyridinedicarboxylic Acid is an inhibitor of histone lysine demethylases and 2-oxoglutarate oxygenases. It structurally mimics 2-oxoglutarate (2-OG) and chelates zinc, thus inhibiting a range of enzymes. As a 2-OG mimic it also inhibits prolyl, collagen and lysyl hydroxylases. It modulates hypoxia-inducible factor turnover, collagen synthesis and plant cell wall formation. It also inhibits zinc-dependent enzymes, like metallo-β-lactamase. It inhibits several Jumonji domain-containing lysine demethylases such as JMJD2A (KDM4A) and KDM4C. It reduced neointimal hyperplasia and inflammation in the carotid arteries of Diabetic Rats. |
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| Size | 100 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,4-Lutidinic acid, 2,4-Dicarboxypyridine, 4-carboxypicolinic acid, histone lysine demethylase inhibitor, Lutidinic acid |
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| Gene, Accession, CAS # | CAS: 499-80-9 |
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| Catalog # | B2809-100 |
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| Order / More Info | 2,4-Pyridinedicarboxylic Acid from BIOVISION, INC. |
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| Product Specific References | n/a |
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