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Product Name | SPDP Crosslinker |
Description | KEY FEATURES: • SPDP contains a dithiopyridyl group which is reactive towards cysteines (-SH groups) and an NHS group, which is useful when targeting primary amines (-NH2 groups) • SPDP releases a byproduct, pyridine-2-thione after reacting with free sulfhydryl groups. By measuring the release of this byproduct at 343 nm, the reaction can be easily followed • Contains a disulfide linkage in its spacer arm with a length of 6.8 A? • The spacer is cleavable with reducing agent, such as DTT, TCEP, etc. APPLICATIONS: • Reversible crosslinking of proteins • N-hydroxysulfosuccinimide (Sulfo-NHS) ester that reacts with primary amines, as found in lysine side chains • Useful for adding sulfhydryl groups to proteins |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-succinimidyl-3-(2-pyridyldithio)propionate; 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester; 3-(2-Pyridyldithio)propionic acid NHS ester |
Gene, Accession, CAS # | CAS: 68181-17-9 |
Catalog # | 2328-50 |
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Order / More Info | SPDP Crosslinker from BIOVISION, INC. |
Product Specific References | n/a |
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