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| Antigenic Specificity | ITM2C |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor® 647 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ITM2C Polyclonal Antibody, Alexa Fluor® 647 Conjugated. • Target Background: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation. |
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| Immunogen | KLH conjugated synthetic peptide derived from human ITM2C. Immunogen Range: 1-50/267 |
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| Other Names | BRI3; BRICD2C; BRICHOS domain containing 2C; Cerebral protein 14; CT-BRI3; E25; E25C ; Integral membrane protein 2C; Integral membrane protein 3; Itm2c; ITM2C_HUMAN; ITM3 antibodyNPD018; Transmembrane protein BRI3. |
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| Gene, Accession # | Gene ID: 81618, SwissProt: Q9NQX7 |
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| Catalog # | bs-11859R-A647 |
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| Price | |
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| Order / More Info | ITM2C Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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