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| Product Name | Recombinant Human Aldehyde oxidase (AOX1 AO), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 24.6kDa. Partial: 236-421aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N-methylphthalazinium, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Aldehyde oxidase 1; Azaheterocycle hydroxylase (EC:1.17.3.-) |
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| Gene, Accession, CAS # | AOX1, UniProt: Q06278 |
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| Catalog # | RPC20908 |
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| Order / More Info | Recombinant Human Aldehyde oxidase (AOX1 AO), partial from BIOMATIK |
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| Product Specific References | n/a |
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