| 产品详情 |
| Edit |   |
|---|
| Product Name | Factor XII (Hageman Factor) BioAssay™ ELISA Kit (Antibodies only) |
|---|
| Description | Factor XII (F.XII, also called Hageman Factor) is a glycoprotein that circulates at levels of 40ug/ml in plasma. Activation of F.XII occurs as a consequence of binding to a negatively charged surface or from the proteolysis by kallikrein to produce alphaXIIa which in turn can activate F.XI to F.XIa. alpha-XIIa can be further cleaved by kallikrein to form alphaXIIa which can feed back to activate more prekallikrein to kallikrein and can also activate F.VII and the classical complement pathway. The natural inhibitors of F.XIIa in plasma are, in order of importance, C1-Inhibitor, alpha 2 Antiplasmin and alpha 2 Macroglobulin. F.XII in plasma and other fluids can be measured by sandwich-style immunoassay. The F.XII is captured onto a microtiter plate coated with affinity purified goat anti-F.XII. The plate is washed to remove unbound protein and the the captured F.XII is then detected with the addition of goat anti-F.XII IgG conjugated to HRP. The plate is again washed and bound antibody c |
|---|
| Size | 1 kit |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | F0019-08 |
|---|
| Price | |
|---|
| Order / More Info | Factor XII (Hageman Factor) BioAssay™ ELISA Kit (Antibodies only) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|