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| Product Name | B7-H4 /VTCN1, mouse recombinant |
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| Description | B7-H4 is a B7 family member that negatively regulates T cell immunity by inhibiting T cell proliferation, cytokine production and cell cycle progression. In vitro, B7-H4 inhibits CD4+ and CD8+ T cell proliferation, cytokine production and generation of alloreactive cytotoxic T cells (CTLs). In vivo, blockade of endogenous B7-H4 by specific monoclonal antibody promotes T cell responses. B7-H4 ia an important negative regulator of innate immunity through growth inhibition of neutrophils. B7-H4 is expressed on some tumor cancer cells. The role of B7-H4 in tumor progression may be to transform precancerous cells and then protect them from immunosurveillance. Purity ≥98% |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | V-set Domain-containing T Cell Activation Inhibitor 1, VTCN1, B7h.5, Immune Costimulatory Protein B7-H4, T Cell Costimulatory Molecule B7x, Protein B7S1 |
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| Gene, Accession, CAS # | Vtcn1, Gene ID: 242122, Accession: Q7TSP5 |
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| Catalog # | P1107-10 |
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| Price | |
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| Order / More Info | B7-H4 /VTCN1, mouse recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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