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| Product Name | Growth Differentiation Factor 3, Recombinant, Mouse (GDF3) |
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| Description | Purity ≥90% as determined by SDS-PAGE (reducing) and visualized by silver stain. Endotoxin: 0.01EU/ug (LAL). GDF3 (previously called Vgr-2) is a TGF-beta superfamily member belonging to the growth/differentiation factor family. GDF3 is expressed in undifferentiated embryonic stem (ES) cells, adipose tissue and the brain. In ES cells, it maintains pluripotency and influences early cell fate decisions. For example, frog embryos injected with GDF3 develop a secondary dorsal axis and deletion of mouse GDF3 can produce defects in the anterior visceral endoderm of the pre-gastrulation embryo. In adipocytes, GDF3 is induced by a high fat diet and promotes adipogenesis. GDF3 has been reported to oppose BMP's functions and to have a nodal-like activity in the early development. The 366aa mouse GDF3 contains a 22aa signal sequence, a 230aa propeptide and a 114aa mature protein that contains one potential N-glycosylation site. Most of GDF3 is present as the prepro form, while mature GDF3 is presu |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 14562, SwissProt: Q07104 |
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| Catalog # | G8989-39B |
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| Order / More Info | Growth Differentiation Factor 3, Recombinant, Mouse (GDF3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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