| 产品详情 |
| Edit |   |
|---|
| Product Name | Caspase-1, human recombinant |
|---|
| Description | Caspase-1 (also know as ICE) is a prototypical member of the caspase-family of cysteine proteases. Caspase-1 exists in cells as an inactive 45 kDa proenzyme. The pro-enzyme is matured by proteolysis to yield large (20 kD) and small (10 kD) subunits. The active caspase-1 is a heterotetramer consisting of two large and two small subunits. To date the regulatory mechanism of caspase-1 activation and the role of caspase-1 in apoptosis are poorly understood. In THP-1 cells, a large proportion of the caspase-1 is present in the inactive proenzyme form. The recombinant active human caspase-1 was expressed in E. coli. The active caspase-1 preferentially cleaves caspase-1 substrates (e.g., YVAD-AFC or YVAD-pNA) and is routinely tested at BioVision f |
|---|
| Size | 100 units |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Caspase-1, CASP-1, Interleukin-1 beta convertase, IL-1BC, IL-1 beta-converting enzyme, p45 |
|---|
| Gene, Accession, CAS # | CASP1, Gene ID: 834, Accession: NP_150634.1 |
|---|
| Catalog # | 1081-100 |
|---|
| Price | |
|---|
| Order / More Info | Caspase-1, human recombinant from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|