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Product Name | Caspase-2, human recombinant |
Description | Caspase-2 (also know as Ich-1, Nedd-2) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-2 also exists in cells as an inactive proenzyme. During apoptosis pro-caspase-2 is processed at aspartate residues by self-proteolysis and/or cleavage by upstream caspases. The processed active caspase-2 is a heterotetramer consisting of two large (19 kDa) and two small (12 kDa) subunits.The recombinant active human caspase-2 was expressed in E. coli. The active caspase-2 preferentially cleaves caspase-2 substrates (e.g., VDVAD-AFC or VDVAD-pNA) and is routinely tested at BioVision for its ability to enzymatically cleave these two substrates Ac-VDVAD-pNA (Cat. #1072-200) or Ac-VDVAD-AFC (1071-200). two large (19 |
Size | 100 units |
Concentration | n/a |
Applications | RUO |
Other Names | Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1 |
Gene, Accession, CAS # | CASP2, Gene ID: 835, Accession: P42575 |
Catalog # | 1082-100 |
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Order / More Info | Caspase-2, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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