| 产品详情 |
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| Product Name | Caspase-3, human recombinant |
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| Description | Caspase-3 (also know as CPP32, Yama and apopain) is a major member of the caspase-family of cysteine proteases. Caspase-3 exists in cells as an inactive 32 kDa proenzyme. During apoptosis procaspase-3 is processed at aspartate residues by self-proteolysis and/or cleavage by upstream caspases, such as caspase-6 (Mch2), caspase-8 (Flice) and grazyme B. The processed form of caspase-3 consists of large (17 kD) and small (11 kD) subunits which associate to form the active enzyme. The active caspase-3 has been shown involving in the proteolysis of several important molecules, such as poly (ADP-ribose) polymerase (PARP), the sterol regulatory element binding proteins (SREBPs), focal adhesion kinase (FAK), and others. The recombinant active human |
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| Size | 5 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1 |
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| Gene, Accession, CAS # | CASP3, Gene ID: 836, Accession: P42574 |
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| Catalog # | 1083-5 |
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| Order / More Info | Caspase-3, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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