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Product Name | Caspase-6, human recombinant |
Description | Caspase-6 (also know as Mch2) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-6 also exists in cells as an inactive proenzyme. During apoptosis procaspase-6 is processed at aspartate residues by self-proteolysis and/or cleavage by another caspase. The processed active form of caspase-6 consists of large (18 kDa) and small (11 kDa) subunits which associate to form the active enzyme. Active caspase-6 has been shown involving in the proteolysis of PARP (poly ADP-ribose polymerase), an enzyme that is involved in DNA repair and henomic maintenance. The recombinant active human caspase-6 was expressed in E. coli. The active caspase-6 is routinely tested at BioVision for its ability to enzymatically clea |
Size | 100 units |
Concentration | n/a |
Applications | RUO |
Other Names | Caspase-6, CASP-6, Apoptotic protease Mch-2 |
Gene, Accession, CAS # | CASP6, Gene ID: 839, Accession: P55212 |
Catalog # | 1086-100 |
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Order / More Info | Caspase-6, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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