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| Product Name | Caspase-8, mouse recombinant |
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| Description | Caspase-8 (also know as FLICE, MASH, Mch5) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-8 also exists in cells as an inactive proenzyme. During apoptosis procaspase-8 is processed at aspartate residues by self-proteolysis and/or cleavage by another caspase. The processed active form of caspase-8 consists of large and small subunits which associate to form the active enzyme. Active caspase-8 has been shown to activate caspase-3 leading to degradation of a variety of cellular target proteins during apoptosis. The recombinant active mouse caspase-8 was expressed in E. coli. The active caspase-8 is routinely tested at BioVision for its ability to enzymatically cleave these two substrates Ac-IETD-pN |
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| Size | 25 units |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Caspase-8, CASP-8, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, FADD-homologous ICE/ced-3-like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, MORT1-associated ced-3 homolog |
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| Gene, Accession, CAS # | CASP8, Gene ID: 12370, Accession: Q3U607 |
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| Catalog # | 1188-25 |
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| Price | |
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| Order / More Info | Caspase-8, mouse recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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