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| Product Name | IL10RA, Recombinant, Human, aa22-235, His-Tag |
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| Description | Purity ~85%(SDS-PAGE). L10RA, also known as Interleukin-10 receptor subunit alpha, is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. It has been shown to interact with Interleukin 10 and Janus kinase 1. Source: Recombinant protein corresponding to aa22-235 from human IL10RA, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~25.2kD (220aa) AA |
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| Size | 50ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL10RA, Recombinant, Human, aa22-235, His-Tag(Interleukin-10 Receptor Subunit alpha, CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R) |
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| Gene, Accession, CAS # | Accession: NP_001549 |
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| Catalog # | 351301 |
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| Order / More Info | IL10RA, Recombinant, Human, aa22-235, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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