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Product Name | FGF-21, murine recombinant |
Description | The FGFs are a family of more than 20 small (~17-26 kDa) secreted peptides. The initial characterization of these proteins focused on their ability to stimulate fibroblast proliferation. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity and, except for FGFR-4, multiple splice isoforms, and FGFR-5, which lacks an intracellular kinase domain. There is growing evidence that FGFRs can be important for regulation of glucose and lipid homeostasis. FGFR-2 appears to be a key molecule during pancreatic development and FGFR-4 has been implicated in cholesterol metabolism and bile acid synthesis. FGF-21 is preferentially expre |
Size | 10 µg |
Concentration | n/a |
Applications | RUO |
Other Names | FGF21, Fibroblast growth factor 21, FGFL, UNQ3115/PRO10196 |
Gene, Accession, CAS # | FGF-21, Gene ID: 56636, Accession: Q9JJN1 |
Catalog # | 4067-10 |
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Order / More Info | FGF-21, murine recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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