| 产品详情 |
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| Product Name | BI-78D3 |
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| Description | An inhibitor of JNK (IC50 = 280 nM); competitive for JNK1 binding with pepJIP1 (IC50 = 500 nM); selective for JNK over p38α, mTOR, and PI3Kα; inhibits c-Jun phosphorylation induced by TNF-α (EC50 = 12.4 µM); restores insulin sensitivity in a mouse model of type 2 diabetes when administered at 25 mg/kg 30 minutes prior to insulin; reduces human prostate strip contractions induced by phenylephrine or norepinephrine when applied at 30 µM and reduces phosphorylation of c-Jun, a JNK substrate, |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | c-Jun N-terminal Kinase Inhibitor X|JNK Inhibitor X |
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| Gene, Accession, CAS # | CAS: 883065-90-5 |
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| Catalog # | 21183-10 |
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| Price | |
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| Order / More Info | BI-78D3 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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