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| Product Name | HBEGF, 63-148aa, Human, His tag, E Coli |
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| Description | MW: 12.1kDa (109aa), confirmed by MALDI-TOF. Purity >80% by SDS-PAGE. HBEGF is growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. This protein promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more pot |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Heparin-binding EGF-like growth factor; DTR; DTS; DTSF; HEGFL] |
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| Gene, Accession, CAS # | HBEGF, Gene ID: 1839, Accession: NP_001936 |
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| Catalog # | MBS205475 |
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| Order / More Info | HBEGF, 63-148aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Higashiyama S., et al. (1991) Science. 251:936-939; Mitamura T., et al. (1995) J. Biol. Chem. 270:1015-1019 |
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