| 产品详情 |
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| Product Name | AM095 |
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| Description | An LPA1 receptor antagonist (IC50s = 25 and 23 nM in CHO cells expressing human or mouse receptors, respectively); selective for LPA1 over LPA2, LPA3, LPA4, and LPA5 (IC50s = >10,000 nM for human LPA2-5); inhibits chemotaxis of CHO cells overexpressing LPA1 and of A2058 human melanoma cells (IC50s = 778 and 233 nM, respectively); prevents LPA-induced increases in plasma histamine levels in mice (ED50 = 8.3 mg/kg); decreases kidney fibrosis in a mouse model of unilateral ureteral obstruction at 30 mg/kg for eight days |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1345614-59-6 AM-095 AM-95 AM95 LPA-1 2 3 4 5 Chinese hamster ovary A-2058 |
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| Gene, Accession, CAS # | CAS: 1228690-36-5 |
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| Catalog # | 22141-5 |
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| Price | |
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| Order / More Info | AM095 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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