| 产品详情 |
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| Product Name | Molindone (hydrochloride) |
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| Description | A dopamine receptor antagonist; selectively inhibits radioligand binding to dopamine D2 receptors in rat brain homogenates (IC50s = 56 and >10,000 nM for D2 and D1 receptors, respectively); inhibits radioligand binding to both D2 and D1 receptors in vivo (ED50s = 4.9 and 51 mg/kg, respectively); reverses D-amphetamine- and apomorphine-induced depression of dopamine neurons and increases dopamine synthesis and dihydroxyphenylacetic acid levels in the striatum and olfactory tubercles in rats from 0.4-0.8 mg/kg; suppresses spontaneous locomotion and blocks conditioned avoidance responses in male mice and female rats; inhibits bromocriptine-induced climbing behavior in mice; increases error rates and reduces response rate in pigeons following learned acquisition from 0.3-5.6 mg/kg, |
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| Size | 5 g |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (±)-Molindone|EN 1733A |
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| Gene, Accession, CAS # | CAS: 15622-65-8 |
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| Catalog # | 23841-5 |
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| Order / More Info | Molindone (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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