| 产品详情 |
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| Product Name | Altretamine |
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| Description | An antineoplastic antiproliferative agent; induces toxicity in an ovarian cancer cell line in vitro when used at a concentration of 10 µg/ml, with radiolabeled thymidine uptake equal to 102 and 75% of controls after 48 and 120 hr, respectively; is demethylated in vivo to form bioactive metabolites, which may exert their cytotoxic effect by cross-linking to DNA or generating formaldehyde; reduces colony survival in A204 cells in an NADP-dependent manner in the presence of an S-9 hepatic activating mixture (88 and 30% colony survival without and with NADP, respectively); inhibits tumor growth in vivo of M5076 reticulum cell sarcoma cells by 70% when used at a dose of 150 mg/kg; acts as a chemosterilant in houseflies; a concentration of 0.05% in fly food prevents hatching and pupation in male and female houseflies |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,4,6-Tris(dimethylamino)-1,3,5-triazine|Hexamethylmelamine|HMM|NSC 13875 |
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| Gene, Accession, CAS # | CAS: 645-05-6 |
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| Catalog # | 23662-50 |
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| Price | |
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| Order / More Info | Altretamine from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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