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Product Name | OX40,Fc, Recombinant, Human (TNFRSF 4, Tumor Necrosis Factor Receptor Superfamily Member 4, CD134) |
Description | Purity >95% (SDS-PAGE). OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully. Biological Activity: Blocks T cell proliferation induced by CD134L. Sequence: Human OX40 (aa 29-214) is fused at the C-terminus to the Fc portion of human IgG1. |
Size | 50ug |
Concentration | n/a |
Applications | n/a |
Other Names | TNFRSF 4, Tumor Necrosis Factor Receptor Superfamily Member 4, CD134 |
Gene, Accession, CAS # | n/a |
Catalog # | 45123 |
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Order / More Info | OX40,Fc, Recombinant, Human (TNFRSF 4, Tumor Necrosis Factor Receptor Superfamily Member 4, CD134) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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