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| Product Name | Recombinant Mouse C-X-C motif chemokine 3 protein (Cxcl3) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE. MW: 12.7kDa. Partial: 26-131aa. C-terminal 6xHis-tagged. Mus musculus (Mouse). Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13Ra1 with low affinity and triggers association of IL4Ra, generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13Ra2 with high affinity, which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Interleukin-13; IL-13; T-Cell Activation Protein P600; Il13; Il-13 |
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| Gene, Accession, CAS # | Il13, UniProt: P20109 |
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| Catalog # | RPC26922 |
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| Price | |
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| Order / More Info | Recombinant Mouse C-X-C motif chemokine 3 protein (Cxcl3) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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