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| Product Name | IMPDH1, 1-514aa, Human, His tag, E Coli |
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| Description | MW: 57.5 kDa (534aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. Inosine-5'-monophosphate dehydrogenase 1, also known as IMPDH1 catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). Also, IMPDH1 is a ubiquitously expressed enzyme, functioning as a homotetramer, which catalyzed the rate-limiting step in de novo synthesis of guanine nucleotides. As such, it plays an important role in cyclic nucleoside metabolism within photoreceptors. Defects in the IMP |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Inosine-5'-monophosphate dehydrogenase 1; IMPD; IMPD1; LCA11; RP10; Inosine-5'-monophosphate dehydrogenase 1 IMP dehydrogenase 1.] |
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| Gene, Accession, CAS # | IMPDH1, Gene ID: 3614, Accession: NP_001136045 |
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| Catalog # | MBS203711 |
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| Order / More Info | IMPDH1, 1-514aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Wang J., et al. (2008) Clin Pharmacol Ther. 83 (5):711-7.; Natsumeda Y., et al. (1990) J Biol Chem. 265 (9):5292-5. |
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