| 产品详情 |
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| Product Name | Ruscogenin |
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| Description | A steroid sapogenin with diverse biological activities; reduces PMA-induced adhesion of HL-60 cells to ECV304 cells (IC50 = 7.76 nM); decreases zymosan A-induced peritoneal leukocyte migration in rats at 5 mg/kg; inhibits ADP-induced platelet aggregation in rats at 12.5 mg/kg; prevents monocrotaline-induced increases in MAP, expression of IL-1β and TNF in plasma and lung, and endothelial cell apoptosis in pulmonary arterioles in a rat model of pulmonary hypertension; reduces proteinuria and renal macrophage infiltration in a rat model of streptozotocin-induced diabetes; decreases gene expression of inflammatory cytokines, dyslipidemia, and liver steatosis in a hamster model of high-fat diet-induced NASH |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 881025-73-6 Ophiopogon Ophiopogonis HL60 ECV-3044 IL1β Radix ophiopogon antiinflammatory antithrombotic TNFα |
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| Gene, Accession, CAS # | CAS: 472-11-7 |
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| Catalog # | 25217-25 |
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| Order / More Info | Ruscogenin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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