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| Product Name | TXN, 1-105aa, Human, His tag, E Coli (Bioactivity Validated) |
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| Description | MW: 13.9 kDa (125aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher). Purity >95% by SDS-PAGE. SQSTM1 is an adapter protein which binds ubiquitin and regulates signaling cascades through ubiquitination. It may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1 and play a role in titin/TTN downstream signaling in muscle cells. This protein also may be involved in cell differentiation, apoptosis, immune response and regulation of K+ |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by BCA assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Thioredoxin; TRX; TRX1; Thioredoxin JW0871; ECK0879; Thioredoxin reductase; FAD/NAD (P)-binding; TRXR.] |
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| Gene, Accession, CAS # | TXN, Gene ID: 7295, Accession: NP_003320 |
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| Catalog # | MBS203573 |
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| Order / More Info | TXN, 1-105aa, Human, His tag, E Coli (Bioactivity Validated) from MYBIOSOURCE INC. |
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| Product Specific References | Pigiet VP., et al. (1986) Proc Natl Acad Sci uSA. 83 (20):7643-7. ; Lundstrom J., et al. (1990) J Biol Chem. 265 (16):9114-20.; |
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