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| Product Name | Recombinant Human Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (ALKBH3) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 35.3kDa. Full Length of Isoform 2: 1-170aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative dethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Alkylated DNA repair protein alkB homolog 3DEPC-1; Prostate cancer antigen 1 |
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| Gene, Accession, CAS # | ALKBH3, UniProt: Q96Q83 |
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| Catalog # | RPC23437 |
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| Order / More Info | Recombinant Human Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (ALKBH3) from BIOMATIK |
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| Product Specific References | n/a |
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