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| Antigenic Specificity | CD272 (BTLA) |
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| Clone | 8F4 |
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| Host Species | Mouse |
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| Reactive Species | mouse |
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| Isotype | IgG1, kappa |
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| Format | biotin conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.25 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD272 (BTLA) Monoclonal Antibody (8F4), Biotin, eBioscience™. B and T lymphocyte attenuator (BTLA) is a 289 amino acid recently identified inhibitory receptor that provides crucial activating or attenuating signals for T cells. It is a third member of co-inhibitory receptors of the CD28 immunoglobulin superfamily with similarities to (CTLA)-4 and (PD)-1 and interacts with a B7 homolog, B7H4. BTLA is constitutively expressed on most CD4+ and CD8+ T cells and its expression progressively decreases upon T cell activation. It remains expressed on Th1 cells but not Th2 cells. BTLA is a unique co-receptor which interacts with the tumor necrosis factor receptor superfamily member herpesvirus entry mediator (HVEM) and this interaction is an i |
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| Immunogen | n/a |
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| Other Names | B and T lymphocyte attenuator; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA1; CD272 |
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| Gene, Accession # | Entrez: 208154; Uniprot: Q7TSA3 |
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| Catalog # | 13-5956-80 |
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| Price | |
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| Order / More Info | CD272 (BTLA) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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