| 产品详情 |
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| Antigenic Specificity | CD86 |
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| Clone | GL-1 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | PE-Dazzle™ 594 conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE/Dazzle™ 594 anti-mouse CD86. CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
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| Immunogen | LPS-activated CBA/Ca mouse splenic B cells |
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| Other Names | B7-2, B70, Ly-58 |
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| Gene, Accession # | Gene ID: 12524 |
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| Catalog # | 105041 |
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| Price | |
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| Order / More Info | CD86 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 17537839,24039898,24912173 |
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