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| Product Name | Recombinant Human G1/S-specific cyclin-D1 |
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| Description | 1-295aa; Full Length. MW: 37.8kD. Purity >90% as determined by SDS-PAGE. Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits mbers of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypopho |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogene] |
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| Gene, Accession, CAS # | CCND1, Gene ID: 595, Accession: NP_444284.1 |
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| Catalog # | MBS966883 |
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| Order / More Info | Recombinant Human G1/S-specific cyclin-D1 from MYBIOSOURCE INC. |
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| Product Specific References | A novel cyclin encoded by a bcl1-linked candidate oncogene.Motokura T., Bloom T., Kim H.G., Jueppner H., Ruderman J.V., Kronenberg H.M., Arnold A.Nature 350:512-515(1991) |
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