产品名称 Nuclear Factor-kappa B Phosphorylation BioAssay™ Kit (NFkB) from UNITED STATES BIOLOGICAL
产品货号 172378
产品价格 现货询价,电话:010-67529703
产品规格 100 tests
产品品牌 UNITED STATES BIOLOGICAL
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Product NameNuclear Factor-kappa B Phosphorylation BioAssay™ Kit (NFkB)
DescriptionNuclear factor-kappa B (NFkB) is a transcription factor that plays a central role in many physiological processes, e.g. inflammation, tumorigenesis, and apoptosis. NFkB is activated by a wide variety of stimuli, including inflammatory cytokines such as TNF-a. NFkB is a dimer composed of members of the Rel family of proteins: p65/RelA, c-Rel, RelB, NFkB1/p50, and NFkB2/p52. Phosphorylation of p65/RelA at Ser-536 results in decreased nuclear export and enhanced p65/RelA-dependent transcription. The cell-based ELISA measures phosphorylated p65(S536) (pNFkB) in whole cells and normalizes the signal to the total protein content. This simple and efficient assay eliminates the need for cell lysate preparation and can be used to study NFkB regulation in short-term and long-term assays. Intended Use: For quantitative fluorescent immunoenzymatic assay of NFkB phosphorylation status in cultured cells. Applications: Determination of NFkB p65 (S536) phosphorylation status in whole cells. Evaluation
Size100 tests
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Catalog #172378
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Order / More InfoNuclear Factor-kappa B Phosphorylation BioAssay™ Kit (NFkB) from UNITED STATES BIOLOGICAL
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