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Product Name | Flavopiridol |
Description | Cell-permeable. Flavopiridol is a synthetic flavonoid compound used as an anticancer agent. It is a serine/threonine kinase inhibitor that broadly targets cyclin-dependent kinases (CDKs), including the cyclin 9/cyclin T complex (pTEF-b), preventing activation of RNA polymerase II. Flavopiridol initiates cell cycle arrest and p53-independent apoptosis through down-regulation of Mcl-1 and X-linked inactivator of apoptosis (XIAP). MW: 401.84. Purity ≥98% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4-chromenone; HMR 1275; L86-8275; NSC 649890 |
Gene, Accession, CAS # | CAS: 146426-40-6 |
Catalog # | 2090-5 |
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Order / More Info | Flavopiridol from BIOVISION, INC. |
Product Specific References | n/a |
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