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Product Name | RWJ-67657 |
Description | RWJ-67657 is a potent inhibitor of the MAP kinases p38α and p38β (IC50s = 1 and 11 µM, respectively, in vitro); inactive against p38γ and p38δ, as well as several other kinases. RWJ-67657 blocks the release of TNF-α and IL-1β from peripheral blood mononuclear cells stimulated with LPS (IC50s = 3 and 11 nM, respectively) and inhibits TNF-α production in LPS-treated mice and rats. MW: 425.5. Purity ≥98% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol |
Gene, Accession, CAS # | CAS: 215303-72-3 |
Catalog # | B2098-5 |
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Order / More Info | RWJ-67657 from BIOVISION, INC. |
Product Specific References | n/a |
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